The PTSim and TOPAS Projects, Bringing Geant4 to the Particle Therapy Clinic
نویسندگان
چکیده
Hyogo Ion Beam Medical Center, 1-2-1, Kouto, Shingu-cho, Ibo-gun, Hyogo, 679-5165, Japan Toyama National College of Technology, 1-2 Ebie-Neriya, Imizu, Toyama, 933-0293, Japan University of California San Francisco, San Francisco, CA, 94143-1708, USA Ashikaga Institute of Technology, 268-1, Omae-cho, Ashikaga, Tochigi, 326-8558, Japan National Institute for Radiology Science, 4-9-1, Anagawa, Inage-ku, Chiba-shi, Chiba, 263-8555, Japan Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan KEK, 1-1 Oho, Tsukuba, Ibaraki, 305-0801, Japan Massachusetts General Hospital, Boston, MA, 02114, USA SLAC, 2575 Sand Hill Road, Menlo Park, CA, 94303, USA Nagoya City, 1-1, Sannomaru 3-chome, Naka-ku, Nagoya, 460-8508, Japan Shikoku University, Ojin-cho, Tokushima-shi, Tokushima, 771-1192, Japan
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Representing Range Compensators in the Topas Monte Carlo System
Double scattering-based proton therapy systems often use patient-specific range compensators for beam modulation. Range compensators adjust the depth in the tissue at which protons reach their Bragg peak. Accurately representing range compensators in Monte Carlo particle transport simulations is a vitally important problem for clinical treatment planning. This paper proposes two new computation...
متن کاملSU-E-T-475: Nano-Dosimetric Track Structure Scoring including Biological Modeling with TOPAS-NBio.
PURPOSE To develop a nano-dosimetric Monte Carlo simulation package, TOPAS-nBio, based on the TOPAS (TOol for PArticle Simulations) framework that is being developed in a collaboration between the Massachusetts General Hospital (MGH), the SLAC National Accelerator Laboratory and the University of California, San Francisco. The goal is to incorporate biological processes on a sub-cell level that...
متن کاملSU-E-T-473: Performance Assessment of the TOPAS Tool for Particle Simulation for Proton Therapy Applications.
PURPOSE The TOPAS Tool for Particle Simulation was developed to make Geant4 Monte Carlo simulation more readily available for research and clinical physicists. Before releasing this new tool to the proton therapy community, several test have been performed to ensure accurate simulations in a variety of proton therapy setups. METHODS TOPAS can model a passive scattering or scanning beam treatm...
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The thymus gland is an endocrine gland that plays an important role in the body’s immunity. Thymus gland cancer happens very rarely and one treatment way is radiation therapy. Due to the location of this gland and its proximity to the sensitive organs, radiation therapy of thymus gland cancer will bring the risk of side effects. In this paper, a Mird phantom is simulated and a modulator and ran...
متن کاملSU-E-T-500: Pencil-Beam versus Monte Carlo Based Dose Calculation for Proton Therapy Patients with Complex Geometries. Clinical Use of the TOPAS Monte Carlo System.
PURPOSE To investigate the necessity of the verification of dose distributions using Monte Carlo (MC) simulations for proton therapy of head and neck patients and other complex patient geometries. METHODS TOPAS, a TOol for PArticle Simulations that makes MC simulations easy-to-use for research and clinical use and is layered on top of Geant4, has been used to simulate the treatments of head a...
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